Fig. 3

Knockdown of TRIB2 inhibited proliferation, migration, invasion, and induced apoptosis of CRC cells. a, b The mRNA and protein levels of TUG1 in CRC cells and normal cells were measured by qRT-PCR and western blot, respectively. c, d The mRNA and protein levels of TUG1 in CRC cells transfected with si-NC or si-TRIB2 were checked by qRT-PCR and western blot, respectively. e, f Proliferation of transfected CRC cells was assessed using MTT assay at different time points. g Flow cytometry was employed to check apoptosis of transfected CRC cells. h, i The abilities of migration and invasion of transfected CRC cells were evaluated by transwell assay. *P < 0.05