Fig. 1
From: Needle tract seeding in renal tumor biopsies: experience from a single institution
Representative images of two cases (a-c and d-f, respectively) demonstrating the histologic evidence of biopsy site changes and tumor seeding along the biopsy site. (a) Low power view showing the primary PRCC, perinephric tissue with biopsy site changes and tumor seeding to the adjacent perinephric adipose tissue beyond the renal capsule; (b) biopsy site changes showing combination of foreign material deposition (asterisk = gelfoam), foreign body reaction, hemosiderin deposition (arrowhead) and fibrosis, as well as a few clusters of tumor cells (arrow) seeded within the biopsy site; (c) High power view highlighting nests of tumor cells (arrow) seeded in the perinephric adipose tissue; (d) Low power view showing the primary PRCC confined within the capsule and perinephric tissue with biopsy site changes with hemorrhage and foreign material deposition (inset); (e) perinephric tissue with foreign body reaction (dashed arrow); (f) High power view highlighting nests of tumor cells (arrow) seeded in the perinephric adipose tissue