From: Detection of BCOR gene rearrangement in Ewing-like sarcoma: an important diagnostic tool
Case | Age/Sex | Location | Size (cm) | BCOR FISH positive | BCOR-CCNB3 RT-PCR positive | neoadjuvant chemotherapy | surgery | Chemotherapy/Radiation (after surgery) | Follow-up (months) | Recurrence and Metastasis (Site) |
---|---|---|---|---|---|---|---|---|---|---|
1 | 14/M | Calcaneus | 5 | Yes | Yes | Yesa | Yes* | Chemotherapya | 46(DOD) | Recurrence & metastasis to lung |
2 | 20/M | Femoral shaft | 12 | Yes | Yes | Yesb | Yes* | Chemotherapya | 40(NED) | No |
3 | 8/M | Fibula | NA | Yes | Yes | No | No | Chemotherapya +Radiationg | 42(NED) | No |
4 | 10/M | Proximal tibia | 16 | Yes | Yes | Yesc | Yes* | Chemotherapyd | 29(NED) | No |
5 | 18/M | Distal femur | NA | Yes | Yes | Yesd | Yes* | Chemotherapyd | 22(NED) | No |
6 | 13/F | Leg | NA | Yes | Yes | Not | Yes | Chemotherapy†a | 9(NED) | No |
7 | 10/M | Leg | NA | Yes | No | Yes†a | ND | ND | 9(AWD) | No |
8 | 11/F | Proximal femur | 9 | Yes | Yes | Yese | Yes* | Chemotherapyf | 7(NED) | No |