Table 2 The kidney biopsy pathology and characteristics of the interstitial infiltrating CLL cells
Case | Glomerular | Interstitium | ||||||
|---|---|---|---|---|---|---|---|---|
Light microscopy | Immunofluorescence | Electron microscopy | Light microscopy | Â | Â | Immunofluo-rescence | Electron microscopy | |
| Â | Injury pattern | Â | Electron dense deposits | The extent of infiltrate CLL cells | Nodular pattern formation | Granulomatous | Â | Â |
1 | Membranous nephritis | IgG++,C3+, C1q+ | Subepithelial deposits | 10% | No | No | Negative | No remarkable change |
2 | Minor change | Negative | No deposits | 90% | Yes | No | Negative | Infiltrating neoplastic cells with crystal formation |
3 | Focal mesangial and endocapillary proliferative glomerulonephritis | C3++ | Mesangial and hump-like subepithelial deposits | 10% | No | No | Negative | No remarkable change |
4 | Membranoproliferative glomerulonephritis | IgG++,IgM+++,C3+,C1q+,κ++,IgG1++,IgG2++ | Subendothelial deposits with microtubule formation | 10% | No | No | Negative | No remarkable change |
5 | Minor change | Negative | No deposits | 90% | Yes | Yes | Negative | No remarkable change |
6 | Membranoproliferative glomerulonephritis | IgG++,C3++,C1q+,κ++IgG1++ | Subendothelial and subepithelial deposits with microtubule formation | 70% | Yes | No | κ++IgG1++ | Infiltrating neoplastic cells with microtubule formation |
7 | Focal mesangial and endocapillary proliferative glomerulonephritis | C3++ | Mesangial and hump-like subepithelial deposits | 50% | Yes | No | Negative | No remarkable change |
8 | Mesangial proliferative glomerulonephritis and thrombotic microangiopathy | C3++ | Mesangial and Subendothelial deposits | 50% | Yes | No | Negative | No remarkable change |
9 | Glomerular hypertrophy | Negative | No deposits | 20% | No | No | Negative | No remarkable change |
10 | Membranoproliferative glomerulonephritis | IgM++,κ++ | Subendothelial and mesangial deposits with microtubule formation | 50% | Yes | No | IgM++,κ++ | No remarkable change |