From: Prognostic significance of the aberrant expression of neuroendocrine markers in melanomas
Clinicopathologic features | No. (%) |
---|---|
Age at surgery (years) | 55.2 (7–87) |
Sex | |
Female | 170 (55.2) |
Male | 138 (44.8) |
Specimen type | |
Biopsy | 84 (27.3) |
Excision | 224 (72.7) |
Location | |
Skin | 33 (10.7) |
Mucosa | 176 (57.1) |
Acral | 30 (9.7) |
Eye | 8 (2.6) |
Other | 61 (19.8) |
Origin | |
Primary | 192 (62.3) |
Distant recurrence | 112 (36.4) |
Local recurrence | 4 (1.3) |
Histological subtype | |
Epithelioid | 128 (46.3) |
Spindle cell | 17 (6.2) |
Small round cell | 96 (34.8) |
Pleomorphic | 10 (3.6) |
Mix type | 25 (9.1) |
Molecular alternations | |
BRAF | 41 (21.0) |
KIT | 12 (6.2) |
PDGFRA | 1 (0.5) |
NRAS | 23 (11.8) |
Stage | |
I–II | 139 (46.8) |
III | 39 (13.1) |
IV | 119 (40.1) |
Overall survival (months) | 16 (0–233) |
Progression-free survival (months) | 10 (1–225) |