From: COVID-19 in pregnancy: placental pathological patterns and effect on perinatal outcome in five cases
 | Case 1 | Case 2 | Case 3 | Case 4 | Case 5 |
---|---|---|---|---|---|
Placental weight,g | 374 | 485 | 465 | 570 | 303 |
Expected weight for gestational age | a481Â +Â 68 | a452Â +Â 58 | a452Â +Â 58 | a452Â +Â 58 | a481Â +Â 68 |
Neonatal weight g | 3790 | 3535 | 2290 | 3720 | 2750 |
Expected weight for gestational age | a3222Â +Â 439 | a3001Â +Â 475 | a3001Â +Â 475 | a3001Â +Â 475 | a3222Â +Â 439 |
MVU lesions | |||||
 Infarction | – | – | – | – | – |
 Increased privillous fibrin deposition | – | – | – | – | – |
 Accelerate villous maturation | – | – | – | – | – |
 Tunney-Parker Change | – | – | + | – | – |
 Distal villous hypoplasia | – | – | + |  |  |
 Intervillous Thrombi | + (1) | + (2) | – | – | + (5) |
FVU lesions | |||||
 Thrombi in fetal circulation | – | – | – | – | – |
 Avascular villi | – | – | – | – | + (2 foci) |
 Delayed villous maturation | + | + | – | + | – |
 Chorangiosis | – | + | – | + | + |
 Phagocytosis of meconium in the amniotic membranes | – | – | – | + | – |
INFLAMMATORY Patterns | |||||
 Chorionamnionitis | – | + | – | – | – |
 Chronic Villitis | – | – | – | + | + |
 Presence of spherical like-coronavirus particles, on ultrastructural analysis | + | + | + | + | + |