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Table 3 Pathological placental patterns

From: COVID-19 in pregnancy: placental pathological patterns and effect on perinatal outcome in five cases

 

Case 1

Case 2

Case 3

Case 4

Case 5

Placental weight,g

374

485

465

570

303

Expected weight for gestational age

a481 + 68

a452 + 58

a452 + 58

a452 + 58

a481 + 68

Neonatal weight g

3790

3535

2290

3720

2750

Expected weight for gestational age

a3222 + 439

a3001 + 475

a3001 + 475

a3001 + 475

a3222 + 439

MVU lesions

 Infarction

–

–

–

–

–

 Increased privillous fibrin deposition

–

–

–

–

–

 Accelerate villous maturation

–

–

–

–

–

 Tunney-Parker Change

–

–

+

–

–

 Distal villous hypoplasia

–

–

+

  

 Intervillous Thrombi

+ (1)

+ (2)

–

–

+ (5)

FVU lesions

 Thrombi in fetal circulation

–

–

–

–

–

 Avascular villi

–

–

–

–

+ (2 foci)

 Delayed villous maturation

+

+

–

+

–

 Chorangiosis

–

+

–

+

+

 Phagocytosis of meconium in the amniotic membranes

–

–

–

+

–

INFLAMMATORY Patterns

 Chorionamnionitis

–

+

–

–

–

 Chronic Villitis

–

–

–

+

+

 Presence of spherical like-coronavirus particles, on ultrastructural analysis

+

+

+

+

+

  1. MVU Maternal vascular Underperfusion
  2. FVU Foetal vascular Underperfusion
  3. aBy Gruenwald P, Minh H Am j Clin Pathol 1960; 34:247–253. doi: https://doi.org/10.1093/ajcp/34.3.247 [13]