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Table 1 Clinicopathological variables of patients with spindle cell variant of medullary thyroid carcinoma

From: Spindle cell variant of medullary thyroid carcinoma: a clinicopathologic study of four cases

Case

Sex

Age

Tumor site

Tumor size

(cm)

Histological type

Immunophenotype

Recurrence

Follow-up

(months)

Status

1

F

54

LLT

2 × 2 × 2.5

spindle cell variant MTC

CT+, CgA +, Syn+, CD56+, TTF-1+, TG-, AE1/AE3+, Ki-67+ (5%)

_

60

Alive

2

M

26

RLT

6 × 3× 3

spindle cell variant MTC

CT+, CgA +, Syn+, CD56+, TTF-1+, TG-, CEA+, AE1/AE3+, SMA-, S-100-,HMB45-,

CD99-, Ki-67+ (5%)

_

7

Alive

3

F

49

LLT

4 × 2× 2

spindle cell variant MTC

CT+, CgA +, Syn+, CD56+, TTF-1+, TG-,

CEA+, vimentin+, SMA-, S-100-, HBME-1-, galectin-3-, CK19-, Ki-67+ (3%)

_

84

Alive

4

M

51

RLT

2.4 × 1.6 × 2.2

spindle cell variant MTC

CT+, CgA +, Syn+, CD56+,TTF-1+, TG-, CEA+ EMA+,vimentin+, SMA-, S-100-, HBME-1-, Ki-67+ (10%)

_

72

Alive

  1. Abbreviations: F female, M male, LLT the left lobe of thyroid, RLT the right lobe of thyroid, MTC Medullary thyroid carcinoma