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Fig. 4 | Diagnostic Pathology

Fig. 4

From: Aurora-A kinase is differentially expressed in the nucleus and cytoplasm in normal Müllerian epithelium and benign, borderline and malignant serous ovarian neoplasms

Fig. 4

Western blotting for Aurora-A and phospho-Thr288-Aurora-A. Western blotting for the localization of total Aurora-A and phospho-Thr288-Aurora-A in the cytoplasmic and nuclear fractions of tumor lysates. Loading of total protein for the cytoplasmic fraction of the serous borderline tumor example appears lower as indicated by low β-actin, however this sample still shows higher cytoplasmic total Aurora-A. The latter is confirmed on another western blot utilizing this sample depicted in Supplemental Fig. 1

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Diagnostic Pathology

ISSN: 1746-1596

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