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Table 1 Summary of pathological, immunohistochemistry, and FISH features of the 13 renal tumorectomies and the left adrenalectomy

From: Clear cell and papillary renal cell carcinomas in hereditary papillary renal cell carcinoma (HPRCC) syndrome: a case report

Specimen number

Laterality

Location

Size* (cm)

Histological type of largest tumor

Type of other tumors

P504S

CK7

CAIX

CD10

VHL deletion

Trisomy 7/17

1

R

upper pole

4

clear cell RCC

 

++ (30%)

+ (5%)

+++ (100%)

++ (80%)

no

no

2

R

external-upper pole

3

clear cell RCC

 

NA

NA

NA

NA

NA

NA

3

R

posterior face

0.3

papillary adenoma

 

NA

NA

NA

NA

NA

NA

4

R

posterior upper pole

0.8

papillary RCC

 

+++ (100%)

+++ (100%)

no

yes

5

R

anterior upper pole

0.3

papillary adenoma

 

+++ (100%)

+++ (100%)

no

no

6

R

lower pole

1

papillary RCC

 

+++ (100%)

+++ (100%)

NA

NA

7

R

lower pole

0.1

papillary adenoma

 

+++ (100%)

+++ (100%)

no

no

8

R

upper pole

1

papillary adenoma

 

NA

NA

NA

NA

NA

NA

9

L

anterior face

2.5

clear cell RCC

 

+ (20%)

+ (5%)

+++ (100%)

++ (80%)

yes

no

10

L

anterior face

0.6

papillary RCC

 

NA

NA

NA

NA

no

yes

11

L

anterior face

0.1

papillary adenoma

papillary adenomas

+++ (100%)

+++ (100%)

+/− (5%)

no

no

12

L

upper pole

1.5

papillary RCC

papillary adenomas

NA

NA

NA

NA

NA

NA

13

L

upper pole

1

papillary RCC

papillary adenomas

+++ (100%)

+++ (100%)

no

7 only

14

L

Adrenal gland

3.1

Clear cell RCC metastasis

 

+ (10%)

+ (10%)

++ (90%)

++ (60%)

no

yes

  1. NA not available, RCC renal cell carcinoma, L left, R right; * size of the largest tumor; +, mild staining; ++, moderate staining; +++, intense staining. The percentage indicated in brackets corresponds to the number of positive cells