Table 1 Associations between SOCS6 expression and clinicopathological variables
High expression (N=102) | Low expression (N=153) | P | |
|---|---|---|---|
Median age (years) | 56 | 56 | 0.28 |
Gender | 0.44 | ||
Male | 55(53.9%) | 91(59.5%) | |
Female | 47(46.1%) | 62(40.5%) | |
Tumor location | 0.48 | ||
Stomach | 66(64.7%) | 94(61.4%) | |
Small intestine | 31(33.3%) | 51(33.3%) | |
Colorectum | 2(2.0%) | 8(5.2%) | |
Median tumor size(cm) | 3.7 | 5.5 | < 0.001 |
Necrosis of tumor | 0.58 | ||
No | 73(71.6%) | 104(68.0%) | |
Yes | 29(28.4%) | 49(32.0%) | |
Mitotic index ( per 50 HPF) | 0.48 | ||
<5 | 65(63.7%) | 92(60.1%) | |
5~10 | 20(19.6%) | 26(17.0%) | |
>10 | 17(16.7%) | 35(22.9%) | |
NIH risk grade | 0.70 | ||
Extremely low | 12(11.8%) | 12(7.8%) | |
Low | 28(27.5%) | 39(25.5%) | |
Moderate | 21(20.6%) | 35(22.9%) | |
High | 41(40.2%) | 67(43.8%) | |
Morphology | 0.57 | ||
Spindle | 93(91.2%) | 144(94.1%) | |
Epithelioid | 3(2.9%) | 2(1.3%) | |
Mixed | 6(5.9%) | 7(4.6%) | |
CD117 | 0.74 | ||
Positive | 99(97.1%) | 147(96.1%) | |
Negative | 3(2.9%) | 6(3.9%) | |
CD34 | 1.00 | ||
Positive | 89(87.3%) | 134(87.6%) | |
Negative | 13(12.7%) | 19(12.4%) | |
DOG1 | 0.73 | ||
Positive | 38(37.3%) | 50(32.7%) | |
Negative | 2(2.0%) | 4(2.6%) | |
Unknown | 62(60.8%) | 99(64.7%) |