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Fig. 4 | Diagnostic Pathology

Fig. 4

From: Clinicopathological and molecular genomic features of monomorphic epitheliotropic intestinal T-cell lymphoma in the Chinese population: a study of 20 cases

Fig. 4

Somatic alterations in STAT5B, TP53 and JAK3 identified in this study. A Four STAT5B-mututed cases harbored three distinctive missense variants, including the common N642H mutation(rs938448224) and two mutations—Y665F(COSM1716592) and A766V(COSM8916674); (B) Four TP53-mututed cases harbored two frameshift variants - V147Afs*19 and I232Sfs, and two missense variants - R248Q and G105C. C Three JAK3-mututed cases harbored three missense variants - M511I(rs752661478), A573V(COSM34215) and R657Q(rs758959409)

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