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Table 1 Characteristics of cases of mucinous carcinoma and high-grade serous carcinoma

From: Comparison of clinical behavior between mucinous ovarian carcinoma with infiltrative and expansile invasion and high-grade serous ovarian carcinoma: a retrospective analysis

Variables

Mucinous carcinoma

Mucinous carcinoma with infiltrative invasion

Mucinous carcinoma with expansile invasion

High-grade serous carcinoma

p-value a

p-value b

p-value c

n =52

n = 27

n = 25

n = 219

Age (years)

           

Median ± SD

49.9 ± 17.7

52.6 ± 17.3

47.0 ± 18.0

58.2 ± 11.5

<0.01

0.11

<0.01

≥60

18

(34.6)

10

(37.0)

8

(32.0)

101

(46.1)

0.16

0.42

0.21

<60

34

(65.4)

17

(63.0)

17

(68.0)

118

(53.9)

   

FIGO stage (%)

        

<0.01

<0.01

<0.01

I

36

(69.2)

16

(59.3)

20

(80.0)

23

(10.5)

   

II

3

(5.8)

1

(3.7)

2

(8.0)

18

(8.2)

   

III

8

(15.4)

7

(25.9)

1

(4.0)

126

(57.5)

   

IV

5

(9.6)

3

(11.1)

2

(8.0)

52

(23.7)

   

Peritoneal cytology (%)

        

<0.01

<0.01

<0.01

Positive

24

(46.2)

14

(51.9)

10

(40.0)

178

(81.3)

   

Negative

28

(53.8)

13

(48.1)

15

(60.0)

41

(18.7)

   

Residual tumor at PDS (%)

        

<0.01

<0.01

<0.01

Yes

13

(25.0)

9

(33.3)

4

(16.0)

152

(69.4)

   

No

39

(75.0)

18

(66.7)

21

(84.0)

67

(30.6)

   

Adjuvant chemotherapy (%)

        

<0.01

<0.01

<0.01

Taxane-platinum therapy

8

(15.4)

6

(22.2)

2

(8.0)

132

(60.3)

   

Platinum-based therapy

26

(50.0)

16

(59.3)

10

(40.0)

65

(29.7)

   

Not administered

18

(34.6)

5

(18.5)

13

(52.0)

22

(10.0)

   

Response rate (%) d

        

0.14

0.02

0.99

CR/PR

6

(54.5)

3

(37.5)

3

(100.0)

105

(77.2)

   

SD/PD

5

(45.5)

5

(62.5)

0

(0.0)

31

(22.8)

   
  1. Abbreviations
  2. SD, standard deviation; FIGO, International Federation of Obstetrics and Gynecology; PDS, primary debulking surgery; CR, complete response; PR, partial response; SD, stable disease; PD, progressive disease
  3. a Mucinous carcinoma vs. high-grade serous carcinoma
  4. b Mucinous carcinoma with infiltrative invasion vs. high-grade serous carcinoma
  5. c Mucinous carcinoma with expansile invasion vs. high-grade serous carcinoma
  6. d One case of mucinous carcinoma with infiltrative invasion, one case of mucinous carcinoma with expansile invasion, and 16 cases of high-grade serous carcinoma with residual tumor at primary debulking surgery did not receive any adjuvant chemotherapy
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Diagnostic Pathology

ISSN: 1746-1596

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