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Fig. 3 | Diagnostic Pathology

Fig. 3

From: Clinicopathological and molecular study of 10 salivary gland clear cell carcinomas, with emphasis on rare cases with high grade transformation and occurring in uncommon sites

Fig. 3

Uncommon histological morphology in CCC. (a) The morphological contrast between the conventional low-grade region on the left and the HGT region on the right and the middle (Case 1, HE× 50). (b) The HGT area showing nuclear pleomorphisms, high nuclear-to-cytoplasmic ratios, high mitotic activity, and necrosis (Case 1, HE× 200). (c) Cystic changes were observed within the tumor nest, forming pseudopapillae (Case 1, HE× 100). (d) Gland-like spaces were focally identified (Case 5, HE× 200). (e) Entrapped non-neoplastic ducts (arrow) (Case 6, HE× 200). (f) Tumor cells were connected to the surface overlying epithelium (Case 7, HE× 100)

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