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Table 3 Immunohistochemistry staining of subungual benign melanocytic proliferation and subungual melanoma in situ

From: Cyclin D1 and PRAME expression in distinguishing melanoma in situ from benign melanocytic proliferation of the nail unit

 

Subungual benign

melanocytic proliferation

(n = 14), n (%)

Subungual

Melanoma in situ

(n = 13), n (%)

cyclin D1 nuclear immunostaining

  

0%

2 (14.3)

2 (15.4)

> 0–10%

0 (0.0)

2 (15.4)

> 10–20%

2 (14.3)

4 (30.8)

> 20–30%

0 (0.0)

0 (0.0)

> 30–40%

0 (0.0)

0 (0.0)

> 40–50%

0 (0.0)

0 (0.0)

> 50–60%

0 (0.0)

0 (0.0)

> 60–70%

0 (0.0)

1 (7.7)

> 70–80%

3 (21.4)

0 (0.0)

> 80–90%

3 (21.4)

1 (7.7)

> 90–100%

4 (28.6)

3 (23.1)

PRAME nuclear immunostaining

  

0%

13 (92.9)

3 (23.1)

> 0–10%

0 (0.0)

0 (0.0)

> 10–20%

1 (7.1)

0 (0.0)

> 20–30%

0 (0.0)

0 (0.0)

> 30–40%

0 (0.0)

0 (0.0)

> 40–50%

0 (0.0)

0 (0.0)

> 50–60%

0 (0.0)

3 (23.1)

> 60–70%

0 (0.0)

0 (0.0)

> 70–80%

0 (0.0)

1 (7.7)

> 80–90%

0 (0.0)

2 (15.4)

> 90–100%

0 (0.0)

4 (30.8)

  1. Abbreviations: PRAME PReferentially expressed Antigen in MElanoma