Table 1 Immunohistochemical staining findings in two cases of gallbladder MiNENs
Antibody | Case 1 | Case 2 | ||
|---|---|---|---|---|
LCNEC | PAC | LCNEC | PAC | |
Syn | diffusely strong positive | – | diffusely strong positive | – |
CgA | weakly positive | – | diffusely strong positive | – |
CEA | – | positive | – | positive |
AE1/AE3 | spotted weakly positive | diffusely strong positive | diffusely strong positive | diffusely strong positive |
LCA | – | – | – | – |
CD117 | – | – | – | – |
CD34 | – | – | – | – |
CK20 | – | – | – | – |
CK7 | – | diffusely positive | – | diffusely positive |
CDX2 | – | – | – | – |
P53 | overexpression | overexpression | – | – |
Ki67 | 80% | 40% | 80% | 60% |