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Fig. 1 | Diagnostic Pathology

Fig. 1

From: Diagnostic utility of CSF1 immunohistochemistry in tenosynovial giant cell tumor for differentiating from giant cell-rich tumors and tumor-like lesions of bone and soft tissue

Fig. 1

Histology and CSF1 IHC of TSGCTs.

a. LTSGCT showed a well-circumscribed mass that consisted of admixture of mononuclear cells, osteoclast-like giant cells, and inflammatory infiltrates with various degrees of collagenous stroma

b. CSF1-positive mononuclear tumor cells were scattered in the tumor

c. DTSGCT was composed of various cells similar to LTSGCT that exhibited sheet proliferation with often cleft-like structures and marked hemosiderin deposits

d. CSF1-positive mononuclear tumor cells were scattered in the tumor

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