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Fig. 4 | Diagnostic Pathology

Fig. 4

From: Diagnostic utility of CSF1 immunohistochemistry in tenosynovial giant cell tumor for differentiating from giant cell-rich tumors and tumor-like lesions of bone and soft tissue

Fig. 4

Histology and CSF1 IHC of undifferentiated pleomorphic sarcoma, leiomyosarcoma, and myxofibrosarcoma

a. Undifferentiated pleomorphic sarcoma showed a solid proliferation of atypical spindle to pleomorphic cells with marked nuclear atypia and nuclear pleomorphism

b. The tumor cells were negative for CSF1.

c. Leiomyosarcoma was composed of a fascicular proliferation of eosinophilic spindle cells with cigar-like elongated nuclei

d. The tumor cells were negative for CSF1.

e. Myxofibrosarcoma was composed of a fascicular proliferation of atypical spindle cells with vesicular nuclei with moderate to severe nuclear pleomorphism. The background was myxoid

f. The tumor cells were negative for CSF1.

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Diagnostic Pathology

ISSN: 1746-1596

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