Fig. 3

sTILs scores compared between pre-NACT and post-NACT tumor tissue. A Table represents mean ± S.E sTILs scores across clinicopathological parameters, including radiological and pathological tumor size, lymph node status for NACT-treated patients, according to the molecular subtypes. The statistical analysis was done using GraphPad Prism v.5. Kruskal Wallis test was performed to compute the significant difference in mean sTILs scores across breast cancer subtypes. The bold font indicates signifiant p-values. B-G Before-after graph depicting sTILs scores for pre- and post-NACT tumor tissue. Individual sTILs scores for each paired sample is shown for patients who received NACT. B; the IDC cohort, C; patients with pCR and D; patients with RD, E; the IDC cohort, E; ER+ subtype, F; HER2+ subtype and G, TNBC subtype. Paired t-test was performed to test the difference in mean between sTILs scores of primary and post-NACT tissue. The red lines indicate patients who showed pathological complete response (pCR), and black lines indicate patients who had the residual disease (RD). The bold font indicates a significant p-value. p-value < 0.05 is represented with ‘*’, < 0.01 with ‘**’ and, < 0.0001 with ‘***’. ns = non-significant. GraphPad Prism v.5 was used for the graphs and statistical calculations