Table 4 Immunohistochemical staining patterns and predicted functional consequence of TP53 mutations within cases with previous neoadjuvant treatment
From: p53 immunostaining pattern is a useful surrogate marker for TP53 gene mutations
Functional consequence | Immunohistochemical pattern of p53 | ||
|---|---|---|---|
Overexpression | Null type | Usual | |
IF-DBD | 14 (73.7) | 0 (0) | 0 (0) |
DISRUPTED | 1 (5.3) | 4 (66.7) | 0 (0) |
Wild type | 4 (2.1) | 2 (33.3) | 1 (100) |
Total | 19 | 6 | 1 |