Table 2 Association between proliferative epithelial changes in tumour adjacent tissue and ER status of the tumour
Proliferative epithelial Changes in tumour Adjacent tissue | ER positive (n = 322) | ER negative(HER2/TN)(n = 98) | P Value | |
|---|---|---|---|---|
Usual ductal hyperplasia | Present | 55 (17.08%) | 12 (12.24%) | 0.252 |
Absent | 267 (82.90%) | 86 (87.75%) | ||
Sclerosing adenosis | Present | 9 (2.79%) | 4 (4.08%) | 0.520 |
Absent | 313 (97.21%) | 94 (95.92%) | ||
Columnar cell lesions | Present | 188 (58.38%) | 47 (47.95%) | 0.069 |
Absent | 134 (41.62%) | 51 (52.05%) | ||
Columnar cell change | Present | 183 (56.83%) | 46 (46.93%) | 0.085 |
Absent | 139 (43.1%) | 52 (53.07%) | ||
Columnar cell hyperplasia | Present | 88 (27.32%) | 17 (17.34%) | 0.04 ** |
Absent | 234 (72.68%) | 81 (82.66%) | ||
Flat epithelial atypia | Present | 54 (16.77%) | 8 (8.16%) | 0.035 ** |
Absent | 268 (83.23%) | 90 (91.84%) | ||
Lobular carcinoma insitu | Present | 10 (3.10%) | 0 (0%) | 0.077 |
Absent | 312 (96.9%) | 98 (100%) | ||
Low grade DCIS | Present | 133 (41.30%) | 11 (11.22%) | 0.000 ** |
Absent | 189 (58.7%) | 87 (88.78%) | ||
Pleomorphic LCIS | Present | 5 (1.55%) | 0 (0%) | 0.215 |
Absent | 317 (98.45%) | 98 (100%) | ||
High grade DCIS | Present | 99 (30.74%) | 43 (43.87%) | 0.016 ** |
Absent | 223 (69.26%) | 55 (56.13%) |