Table 3 Association between proliferative epithelial changes in tumour adjacent tissue and Nottingham grade of the tumour
Proliferative epithelial changes in tumour adjacent tissue | Nottingham grade | P Value | ||
|---|---|---|---|---|
Low grade | High grade | |||
Grade 1 &2 (n=182) | Grade 3 (n=238) | |||
Usual ductal hyperplasia | Present | 35 (19.23%) | 32 (13.44%) | 0.109 |
Absent | 147 (80.77%) | 206 (86.56%) | ||
Sclerosing adenosis | Present | 6 (3.29%) | 7 (2.94%) | 0.835 |
Absent | 176 (96.71%) | 231 (97.06%) | ||
Columnar cell lesions | Present | 116 (63.73%) | 119 (50%) | 0.005** |
Absent | 66 (36.27%) | 119 (50%) | ||
Columnar cell change | Present | 113 (62.08%) | 116 (48.73%) | 0.006** |
Absent | 69 (37.92%) | 122 (51.27%) | ||
Columnar cell hyperplasia | Present | 53 (29.12%) | 52 (21.84%) | 0.088 |
Absent | 129 (70.88%) | 186 (78.16%) | ||
Flat epithelial atypia | Present | 34 (18.68%) | 28 (11.76%) | 0.048** |
Absent | 148 (81.32%) | 210 (88.24%) | ||
Lobular carcinoma insitu | Present | 7 (3.84%) | 3 (1.26%) | 0.085 |
Absent | 175 (96.16%) | 235 (98.74%) | ||
Low grade DCIS | Present | 95 (52.19%) | 49 (20.58%) | 0.000 ** |
Absent | 87 (47.81%) | 189 (79.42%) | ||
Pleomorphic LCIS | Present | 1 (0.54%) | 4 (1.68%) | 0.289 |
Absent | 181 (99.46%) | 234 (98.32%) | ||
High grade DCIS | Present | 33 (18.13%) | 109 (45.79%) | 0.000** |
Absent | 149 (81.87%) | 129 (54.21%) | ||