Table 1 Clinical characteristics of patients with ENKTCL-NT combined with peripheral neuropathy
Authors, year | Age/Sex | Country | Initial symptoms | Nerve involvement site | Primary site of ENKTCL-NT | Treatment | Therapeutic effect | Duration of Follow-up (months) | Survival Status |
|---|---|---|---|---|---|---|---|---|---|
Wills A J, et al., 2008 [6] | 29/F | UK | Numbness and weakness of lower limbs and face | Facial and lumbar nerve | Ovarian adnexa | Steroidsï¼›chemotherapy | Complete remission | 15 | Survival |
Morita M,et al., 2009 [7] | 67/M | Japan | Leg pain, bladder and bowel dysfunction | Cauda Equina | Cauda Equina | Radiotherapy | Disease progression | 14 | Died |
Agrawal S, et al., 2013 [8] | 57/F | Singapore | Swelling and numbness in the right forearm | Ulnar nerve | NA | Chemotherapy | Complete remission | 12 | Survival |
Aynardi M,et al., 2018 [9] | 59/F | USA | Pain and numbness in right ankle with ulcer | Posterior tibial nerve | Nasal cavity | Radiotherapy+ Chemotherapy | Complete remission | 12 | Survival |
Our case, 2022 | 17/F | China | Rash， Numbness, and weakness in both hands | Peripheral nerves of upper and lower extremities | Skin | Steroids；chemotherapy | Partial remission | 5 | Survival |