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Table 4 The difference in the number of cases in the two categories in relation to the cut-off of IMP3 overall positivity. P-values are based on chi-squared test

From: A comprehensive immunohistochemical analysis of IMP2 and IMP3 in 542 cases of ovarian tumors

 

cut-off = 5%

cut-off = 10%

cut-off = 50%

N positive

N negative

p-value

N positive

N negative

p-value

N positive

N negative

p-value

HGSC x LGSC

  

<  0.001

  

<  0.001

  

<  0.001

 HGSC

76 (67%)

38 (33%)

 

71 (62%)

43 (38%)

 

48 (42%)

66 (58%)

 

 LGSC

23 (23%)

77 (77%)

 

12 (12%)

88 (88%)

 

4 (4%)

96 (96%)

 

HGSC x CCC

  

0.965

  

0.819

  

0.979

 HGSC

76 (67%)

38 (33%)

 

71 (62%)

43 (38%)

 

48 (42%)

66 (58%)

 

 CCC

83 (67%)

41 (33%)

 

79 (64%)

45 (36%)

 

52 (42%)

72 (58%)

 

HGSC x EC

  

<  0.001

  

0.001

  

0.119

 HGSC

76 (67%)

38 (33%)

 

71 (62%)

43 (38%)

 

48 (42%)

66 (58%)

 

 EC

21 (39%)

33 (61%)

 

19 (35%)

35 (65%)

 

16 (30%)

38 (70%)

 

EC x CCC

  

<  0.001

  

<  0.001

  

0.120

 EC

21 (39%)

33 (61%)

 

19 (35%)

35 (65%)

 

16 (30%)

38 (70%)

 

 CCC

83 (67%)

41 (33%)

 

79 (64%)

45 (36%)

 

52 (42%)

72 (58%)

 

MC x HGSC

  

0.079

  

0.064

  

0.044

 MC

28 (82%)

6 (18%)

 

27 (79%)

7 (21%)

 

21 (62%)

13 (38%)

 

 HGSC

76 (67%)

38 (33%)

 

71 (62%)

43 (38%)

 

48 (42%)

66 (58%)

 

MC x EC

  

<  0.001

  

< 0.001

  

0.003

 MC

28 (82%)

6 (18%)

 

27 (79%)

7 (21%)

 

21 (62%)

13 (38%)

 

 EC

21 (39%)

33 (61%)

 

19 (35%)

35 (65%)

 

16 (30%)

38 (70%)

 

MC x CCC

  

0.082

  

0.084

  

0.040

 MC

28 (82%)

6 (18%)

 

27 (79%)

7 (21%)

 

21 (62%)

13 (38%)

 

 CCC

83 (67%)

41 (33%)

 

79 (64%)

45 (36%)

 

52 (42%)

72 (58%)

 
  1. HGSC high grade serous carcinoma, LGSC low grade serous carcinoma, mSBT micropapillary serous borderline tumor, EC endometrioid carcinoma, CCC clear-cell carcinoma, MBT mucinous borderline tumor, MC mucinous carcinoma