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Table 4 The number of CIN1-CIN3 cases and RNAscope positive cases in the test group

From: CIN grades possessing different HPV RNA location patterns and RNAscope is helpful tool for distinguishing squamous intraepithelial lesions in difficult cervical cases

 

RNAscope + cases/Total

Total

CIN1

CIN2

CIN3

Test-A(n = 13)

2/4

1/6

3a/3

6/13

Test-B(n = 8)

1/2

2/5

1/1

4/8

Test-C(n = 15)

2b/7

1/5

3/3

6/15

Total(n = 35)

5/13

4/16

6/6

15/35

  1. Test-A group: P16-, Ki-67 + , HPV + 
  2. Test-B group: P16 + , Ki-67- or < 10%, HPV + 
  3. Test-C group: P16 + , Ki-67 + , HPV- or P16-, Ki-67-, HPV + 
  4. aP16 mottled positive at CIN3 was classified as group Test-A
  5. bThis group included 1 case of LR-HPV-HPV
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Diagnostic Pathology

ISSN: 1746-1596

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