Table 3 Overview of the expression of 26 markers based on categorical scoring: positive (≥ 5% positive tumor cells) vs. negative (< 5% positive tumor cells) cases

ER

 < 0.001

0.004

1.000

n positive

101 (89%)

93 (99%)

39 (100%)

n negative

13 (11%)

1 (1%)

0 (0%)

PR

 < 0.001

0.005

 < 0.001

n positive

36 (32%)

49 (51%)

32 (82%)

n negative

78 (68%)

48 (49%)

7 (18%)

PAX8

1.000

1.000

1.000

n positive

113 (99%)

95 (99%)

39 (100%)

n negative

1 (1%)

1 (1%)

0 (0%)

ARID1A

0.068

0.082

1.000

n positive

112 (98%)

88 (93%)

36 (95%)

n negative

2 (2%)

7 (7%)

2 (5%)

PTEN

 < 0.001

 < 0.001

1.000

n positive

96 (84%)

95 (99%)

38 (100%)

n negative

18 (16%)

1 (1%)

0 (0%)

HNF1B

0.801

0.538

0.294

n positive

34 (30%)

24 (26%)

12 (35%)

n negative

80 (70%)

69 (74%)

22 (65%)

Napsin A

NULL

NULL

NULL

n positive

0 (0%)

0 (0%)

0 (0%)

n negative

114 (100%)

96 (100%)

39 (100%)

CDX2

0.334

0.626

1.000

n positive

3 (3%)

1 (1%)

0 (0%)

n negative

111 (97%)

96 (99%)

39 (100%)

NTRK

0.458

1.000

NULL

n positive

1 (1%)

0 (0%)

0 (0%)

n negative

113 (99%)

96 (100%)

39 (100%)

MUC4

0.181

0.377

1.000

n positive

4 (4%)

1 (1%)

0 (0%)

n negative

110 (96%)

96 (99%)

39 (100%)

BRG1

1.000

0.459

1.000

n positive

114 (100%)

96 (99%)

39 (100%)

n negative

0 (0%)

1 (1%)

0 (0%)

PAX2

 < 0.001

 < 0.001

0.118

n positive

47 (41%)

64 (67%)

30 (81%)

n negative

67 (59%)

31 (33%)

7 (19%)

Mammaglobin

0.009

0.002

0.050

n positive

16 (14%)

2 (2%)

4 (11%)

n negative

98 (86%)

94 (98%)

33 (89%)

SATB2

0.475

0.728

0.557

n positive

5 (4%)

3 (3%)

0 (0%)

n negative

109 (96%)

94 (97%)

39 (100%)

RB1

 < 0.001

0.002

1.000

n positive

97 (86%)

90 (98%)

39 (100%)

n negative

16 (14%)

2 (2%)

0 (0%)

AMACR

0.588

0.461

0.508

n positive

8 (7%)

10 (10%)

2 (5%)

n negative

106 (93%)

86 (90%)

37 (95%)

TTF1

0.456

1.000

NULL

n positive

1 (1%)

0 (0%)

0 (0%)

n negative

113 (99%)

97 (100%)

39 (100%)

Cyclin E1

 < 0.001

 < 0.001

0.743

n positive

108 (95%)

68 (73%)

26 (70%)

n negative

6 (5%)

25 (27%)

11 (30%)

Statmin

 < 0.001

 < 0.001

0.431

n positive

110 (96%)

66 (70%)

24 (63%)

n negative

4 (4%)

28 (30%)

14 (37%)

BCOR

NULL

NULL

NULL

n positive

0 (0%)

0 (0%)

0 (0%)

n negative

114 (100%)

97 (100%)

39 (100%)

L1CAM

0.002

0.045

0.037

n positive

39 (34%)

20 (21%)

2 (5%)

n negative

75 (66%)

75 (79%)

35 (95%)

LMP2

0.002

0.009

NULL

n positive

106 (93%)

95 (100%)

38 (100%)

n negative

8 (7%)

0 (0%)

0 (0%)

CD44

 < 0.001

 < 0.001

1.000

n positive

30 (26%)

3 (3%)

1 (3%)

n negative

84 (74%)

90 (97%)

36 (97%)

Ki67

 < 0.001

 < 0.001

0.573

n positive

109 (96%)

16 (18%)

5 (14%)

n negative

5 (4%)

75 (82%)

32 (86%)

p16^a

 < 0.001

 < 0.001

NULL

n positive

77 (68%)

0 (0%)

0 (0%)

n negative

37 (32%)

96 (100%)

38 (100%)

p53^a

 < 0.001

 < 0.001

NULL

n positive

98 (91%)

0 (0%)

0 (0%)

n negative

10 (9%)

96 (100%)

38 (100%)