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Table 2 Pathological characteristics of the Six Metastases to the Kidney from Primary Lung Cancer Patients

From: Metastases to the kidney from primary lung cancer : clinicopathological analysis of six cases in a single center

sr

No.

Lung

Histological grading

Lymph node metastasis

Vasular

invasion

Clinical Staging

IHC

Ki67

Renal

IHC

Histological grading

Vasular

invasion

Ki67

1

ACA

P

Y

UN

IVA

CK7+,TTF-1+,NapsinA+,

P63-, P40-,Syn-,

CgA-,CD56-

80%

ACA

CK(AE1/AE3)+,CK7+,

TTF-1+,NapsinA+, PAX-8-,GATA3-

P

Y

60%

2

ACA

M

Y

Y

IIB/

pT1cN1M0

CK7+,TTF-1+,NapsinA+,

P63-, P40-,Syn-,

CgA-,CD56-

10%

ACA

CK(AE1/AE3)+,TTF-1+, NapsinA+,PAX-8-

P

N

3%

3

Small-cell CA

P

Y

UN

IIIB

TTF-1+,Syn+,CgA+,

CD56+,CK7-,NapsinA-,

P63-, P40-

90%

Small-cell CA

Syn+, CgA+,

TTF-1+,GATA3-

P

UN

60%

4

SCC

P

UN

UN

IIB

P63+,P40+,TTF-1-,CK7-,

NapsinA-,Syn-,CgA-,CD56-

40%

SCC

CK(AE1/AE3)+,P63+,

P40+,PAX-8-,GATA3-

P

UN

30%

5

ACA

M

UN

UN

IIIA

CK7+,TTF-1+,NapsinA+,

P63-, P40-,Syn-,

CgA-,CD56-

70%

ACA

CK(AE1/AE3) +, TTF-1 +, NapsinA+, GATA3-

M

UN

40%

6

ACA

M

N

N

IA3 /

pT1cN0M0

CK7+,TTF-1+,NapsinA+,

P63-, P40-,Syn -,

CgA-,CD56-

60%

ACA

CK7+,TTF-1+,

NapsinA+,PAX-8-,GATA3-

M

N

20%

  1. ACA, adenocarcinoma; CA, carcinoma; SCC, squamous-cell CA;N,no;Y,yes;UN, unknown;P,poorly differentiated;M, moderately differentiated,CK, cytokeratin; TTF-1, thyroid transcription factor-1; NapsinA,Aspartic proteinase napsin;PAX-8, paired box gene 8;GATA3 ,gata binding protein 3;Syn,synapsin;CgA, chromogranin A