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Fig. 2 | Diagnostic Pathology

Fig. 2

From: Pathological characteristics and immune microenvironment of SMARCA4-deficient undifferentiated uterine sarcoma

Fig. 2

Hematoxylin-eosin and immunohistochemical staining of SDUS lesions. (A) Tumor cells invading blood vessels (40×, red arrow); (B) Tumor necrosis area (40×); (C) Tumor involved normal endometrial glands with tumor necrosis (100×); (D) Tumor cells were epithelioid medium-to-large cells with local rhabdoid morphology (200×). Immunohistochemical staining for the Ki-67 proliferation marker immunohistochemistry showing a high percentage (60%) of positively stained cells, along with the observation of INI-1 expression, local of expression of CD10, and the lack of expression of BRG1, CK, SYN, desmin, and ER (200×)

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