Table 3 Characterization of gene fusions detected among 105 OCCCs.
Fusion | Fusion (number of fusion reads/all reads from 5’gene) | Reading frame | chromosomes | strand | exon-exon boundary† | references |
|---|---|---|---|---|---|---|
LAMB1::MET | LAMB1[NM_002291.3]:r.1_560_MET[NM_001127500.3]:r.3181_6876 (3729/6307) | IF | 7;7 | -;+ | e5-e13 | novel |
CCDC3::AKT3 | CCDC3[NM_031455.4]:r.1_692_AKT3[NM_005465.7]:r.363_7281 (112/602) | FS | 10;1 | -;- | e2-e3 | novel |
CAPZA2::MET | CAPZA2[NM_006136.3]:r.1_180_MET[NM_001127500.3]:r.1789_6876 (1093/3793) | FS | 7;7 | +;+ | e3-e4 | yes |
LGALS3::EZH2 | LGALS3[NM_002306.4]:r.1_650_EZH2[NM_004456.4]:r.440_2723 (33/47) | IF | 14;7 | +;- | e5-e4 | novel |
ST7::MET | ST7[NM_021908.3]:r.1_191_MET[NM_001127500.3]:r.1597_6876 (56/766) | FS | 7;7 | +;+ | e1-e3 | yes* |
ST7::MET | ST7[NM_021908.3]:r.1_191_MET[NM_001127500.3]:r.3034_6876 (514/4312) | FS | 7;7 | +;+ | e1-e12 | yes* |
ARID1A::MIA2 | ARID1A[NM_006015.6]:r.1_1526_MIA2[NM_005930.4]:r.139_3630 (22/260) | IF | 1;14 | +;+ | e1-e2 | novel |
DHX15::ATR | DHX15[NM_001358.3]:r.1_1646_ATR[NM_001184.4]:r.7071_8158 (42/588) | IF | 4;3 | -;- | e8-e42 | novel |
ERBB4::IKZF2 | ERBB4[NM_005235.3]:r.1_354_IKZF2[NM_016260.3]:r.412_9515 (258/641) | IF | 2;2 | -;- | e1-e4 | yes |
NBN::CNGB3 | NBN[NM_002485.4]:r.1_1234_CNGB3[NM_019098.4]:r.387_4347 (66/71) | IF | 14;7 | -;- | e9-e4 | novel |
ESR1::ARMT1 | ESR1[NM_001122742.1]:r.1_1466_ARMT1[NM_024573.3]:r.122_2397 (51/305) | FS | 14;7 | +;+ | e6-e2/3 | yes |
NF1::GOSR1 | NF1[NM_000267.3]:r.1_443_GOSR1[NM_004871.3]:r.179_5993 (942/20) | FS | 17;17 | +;+ | e1-e3 | novel |
TFG::ADGRG7 (2x) | TFG[NM_001007565.2]:r.1_453_ADGRG7[NM_032787.3]:r.372_3128 | IF | 3;3 | +;+ | e3-e2 | yes |