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Fig. 1 | Diagnostic Pathology

Fig. 1

From: The multi-omics analyses of acsl1 reveal its translational significance as a tumor microenvironmental and prognostic biomarker in clear cell renal cell carcinoma

Fig. 1

ACSL1 expression in RCC tissues and pan-carcinoma. (A) ACSL1 profiles in tumorous and normal tissues of pan-cancer data from the Cancer Genome Atlas (TCGA). (B) ACSL1 mRNA expression between ccRCC and matched healthy tissues in TCGA data sets. (C) ACSL1 mRNA expression in ccRCC and matched normal tissues in GSE40435 data sets. (D) Differential expression of ACSL1 between ccRCC and normal tissues in GSE53757 data. (E) ACSL1 mRNA expression levels in the six RCC and matched paracancerous tissues. (F) Differential expression of ACSL1 in ccRCC cell lines and renal tubular epithelial cell HK-2. (G) Immunohistochemical images from the HPA data sets show ACSL1 expression in RCC tissues and normal renal tissues. (H) Protein expression of ACSL1 in ccRCC tissues and neighboring healthy tissues from six patients in West China Hospital. N1-6: paracancerous tissues of patients 1–6, T1-6: cancer tissues of patients 1–6. the bands gray value of N1-6 significantly higher than the T1-6. The normalized gray value of 29 pairs of renal carcinoma tissues after quantitative analysis were shown on the right. (I) Protein expression of ACSL1 in tumor and normal tissues in ccRCC data from CPTAC. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001. ns, not significant

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