Fig. 3From: The multi-omics analyses of acsl1 reveal its translational significance as a tumor microenvironmental and prognostic biomarker in clear cell renal cell carcinomaDNA methylation modification was associated with ACSL1 silence. (A) Changes of 8 DNA methylation-associated genes between ACSL1-low and ACSL1-high expression subgroups in ccRCC. Correlation of ACSL1 mRNA expression with TET2, TET3, TRDMT1 on the right. *P < 0.05; **P < 0.01; ***P < 0.001; -, not significant. (B) Comparison of DNA methylation probes between healthy and tumorous samples: cg03498175 (ACSL1) and cg08823975 (ACSL1) exhibited higher methylation levels in tumor tissues, P < 0.0001. (C) A waterfall plot of the methylation level of the ACSL1 subregions in ccRCC is presented. The association between methylation levels of different ACSL1 probes with expression and survival were analyzedBack to article page