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Fig. 5 | Diagnostic Pathology

Fig. 5

From: The multi-omics analyses of acsl1 reveal its translational significance as a tumor microenvironmental and prognostic biomarker in clear cell renal cell carcinoma

Fig. 5

Enrichment analysis of ACSL1 high-expression group in ccRCC and the relationship of ACSL1 expression in ccRCC with the ferroptosis-related genes. (A) The volcano map showed differential genes in ACSL1-high and ACSL1-low subgroups. (B-C) Enrichment analysis of KEGG and GO for genes up-regulated in ACSL1 high-expression group. (D) Ferroptosis-associated genes in ACSL1 high-,low-expression groups in ccRCC and in normal renal tissues group. *P < 0.05, **P < 0.01, ***P < 0.001. (E) The link between ferroptosis-related genes in the ACSL1 high- and low-expression group. (F-G) Univariate Cox regression analysis of age, clinical stage, tumor grade and ten ferroptosis-related genes with the smallest p-value in predicting prognosis in ACSL1-high and ACSL1 low-expression group in ccRCC

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Diagnostic Pathology

ISSN: 1746-1596

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