Table 2 Relationship between MCM4 expression and various cancer related molecules in 124 upper tract urothelial carcinoma cases

Ki-67

 Positive (20%<)

29 (67%)

6

0.0036

 Negative (20%>)

48 (54%)

41

PD-L1 in TCs

 Positive

14 (78%)

4

0.1904

 Negative

63 (59%)

43

PD-L1 in TILs

 Positive

26 (68%)

12

0.4228

 Negative

51 (59%)

35

CD44v9

 Positive

16 (67%)

8

0.8129

 Negative

50 (63%)

29

HER2

 Positive

18 (82%)

4

0.0355

 Negative

59 (58%)

43

EGFR

 Positive

25 (81%)

6

0.0181

 Negative

52 (55%)

41

FGFR3

 Positive

25 (69%)

11

0.3139

 Negative

52 (59%)

36

p53

 Positive

31 (89%)

4

< 0.0001

 Negative

46 (52%)

43

GATA3

 Positive

68 (61%)

43

0.7647

 Negative

9 (69%)

4

CK 5/6

 Positive

17 (65%)

9

0.8213

 Negative

60 (61%)

38