Table 4 Comparison of univariate and multivariate logistic regression analyses for identification of independent predictive marker of high grade urothelial carcinoma in MCM4 expression and other molecules

MCM4

 Negative

1 (Reference)

< 0.0001

1 (Reference)

0.0002

 Positive

6.97 (3.09–15.71)

5.18 (2.11–12.70)

Ki-67

 Negative

1 (Reference)

0.0244

1 (Reference)

0.8086

 Positive

2.56 (1.10–5.94)

1.13 (0.41–3.11)

PD-Ll in TCs

 Negative

1 (Reference)

0.0073

1 (Reference)

0.1311

 Positive

4.81 (1.32–17.61)

2.98 (0.67–13.27)

PD-L1 in TILs

 Negative

1(Reference)

0.0200

1 (Reference)

0.3668

 Positive

2.57 (1.13–5.83)

1.60 (0.57–4.47)

CD44v9

 Negative

1(Reference)

0.0768

 Positive

2.37 (0.88–6.34)

HER2

 Negative

1(Reference)

0.0697

 Positive

2.46 (0.89–6.81)

EGFR

 Negative

1 (Reference)

0.0442

1 (Reference)

0.5803

 Positive

2.39 (1.01–5.74)

1.33 (0.48–3.64)

FGFR3

 Negative

1 (Reference)

0.6996

 Positive

1.17 (0.53–2.56)

p53

 Negative

1 (Reference)

0.0004

1 (Reference)

0.1382

 Positive

4.68 (1.85–11.84)

2.19 (0.76–6.29)