Table 5 Diagnostic accuracy of MCM4 expression and cytology for the detection of urothelial carcinoma in urine cytology cases
|  | Cytology | MCM4 | Cytology + MCM4 |
|---|---|---|---|
Sensitivity, % (95% CI) | 58 (49–61) | 69 (59–77) | 89 (79–95) |
Specificity, % (95% CI) | 96 (89–99) | 80 (71–88) | 79 (70–84) |
PPV, % (95% CI) | 94 (80–99) | 77 (65–86) | 79 (71–85) |
NPV, % (95% CI) | 71 (65–73) | 74 (65–81) | 88 (78–95) |
AUC (95% CI) | 0.77 (0.69–0.83) | 0.75 (0.66–0.82) | 0.84 (0.75–0.89) |