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Fig. 1 | Diagnostic Pathology

Fig. 1

From: Effect and mechanism of HMG-CoA reductase inhibitor on the improvement of elderly essential hypertension-induced vascular endothelial function impairment based on the JAK/STAT pathway

Fig. 1

HMG-CoA reductase inhibitor mediates the JAK/STAT3 pathway to improve vascular endothelial function impairment in elderly patients with essential hypertension. A. Blood pressure (SBP and DBP) levels in each group of rats. B. Blood lipid levels in each group of rats were detected by an automatic biochemical analyzer. C. Ultrasound detection of cardiac function-related indices in each group of rats. D. Left ventricular mass index in each group of rats. E. ELISA detection of inflammatory factor levels in each group of rats. F. ELISA detection of vascular endothelial function-related indices in each group of rats. G. Western blot detection of p-JAK2, JAK2, p-STAT3, and STAT3 protein expression in each group of rats. n = 10. * p < 0.05 vs. Before treatment; # p < 0.05 vs. Control group

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