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Fig. 1 | Diagnostic Pathology

Fig. 1

From: DNA damage response and repair gene mutations are associated with tumor mutational burden and outcomes to platinum-based chemotherapy/immunotherapy in advanced NSCLC patients

Fig. 1

The mutational landscape of advanced NSCLC without EGFR or ALK gene alterations. (A) The frequently mutated genes of advanced NSCLC without EGFR or ALK gene alterations. (B) The mutated DDR genes and clinical features of advanced NSCLC without EGFR or ALK gene alterations. (C) The interaction between DDR genes and frequently mutated genes. (D) The percentage of patients with metastasis in DDR negative and DDR positive patients. (E) The percentage of DDR positive patients in LUAD and LUSC. (F) The percentage of MMR-positive, NER-positive, HR-positive, FA-positive, CCK-positive, BER -positive, and NHEJ-positive patients in LUAD and LUSC.

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Diagnostic Pathology

ISSN: 1746-1596

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