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Table 1 Patient demographics and clinical characteristics

From: DNA damage response and repair gene mutations are associated with tumor mutational burden and outcomes to platinum-based chemotherapy/immunotherapy in advanced NSCLC patients

Clinical Characteristics

All (n = 49)

Age (Median = 62)

 

<65

33 (67.3%)

≥ 65

16 (32.7%)

Gender

 

Male

34 (69.4%)

Female

15 (30.6%)

Smoking status

 

Smoker

23 (46.9%)

Non-smoker

26 (53.1%)

Stage

 

III

8 (16.3%)

IV

41 (83.7%)

Metastasis

 

0

8 (16.3%)

1

19 (38.8%)

> 1

22 (44.9%)

NSCLC subtype

 

Adenocarcinoma

35 (71.4%)

Squamous

13 (26.5%)

other

1 (2.0%)

Response

 

CR

1 (2.0%)

PR

21 (42.9%)

SD

19 (38.8%)

PD

6 (12.2%)

NA

2 (4.1%)

Therapy

 

Platinum-based chemotherapy

13 (26.5%)

Platinum-based chemotherapy/immunotherapy

32 (63.3%)