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Table 2 Association between clinical characteristics and DDR gene mutations in advanced NSCLC patients

From: DNA damage response and repair gene mutations are associated with tumor mutational burden and outcomes to platinum-based chemotherapy/immunotherapy in advanced NSCLC patients

 

Negative

Positive

Odd ratio

P value

Age

    

< 65

20

13

1.19

1

>=65

9

7

  

Gender

    

female

8

7

0.71

0.75

male

21

13

  

Smoking history

    

Never_smoking

13

13

0.45

0.24

Smoking

16

7

  

Tumor size

    

Small

12

12

0.48

0.25

Big

17

8

  

Metastasis

    

Never_metastasis

2

6

0.18

0.0497

Metastasis

27

14

  

Therapy

    

Platinum-based chemotherapy/immunotherapy

21

11

2.97

0.11

Platinum-based chemotherapy

5

8