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Table 2 Clinicopathological features of the current cases

From: Circularity of islets is a distinct marker for the pathological diagnosis of adult non-neoplastic hyperinsulinemic hypoglycemia using surgical specimens

(A) ANHH cases.

 

CASE 1

CASE 2

CASE 3

CASE 4

 

Age (years)/Gender

24/M

54/M

49/F

34/F

 

Symptom

HH

Hypoglycemia with LOC

Hypoglycemia with headache and LOC after TG

HH with arrhythmia

 

Clinical Diagnosis

ANHH

Insulinoma

ANHH

Insulinoma

 

CT scan

No nodule

No nodule

No nodule

No nodule

 

Surgical procedure

DP

DP

DP

DP

 

Postoperative course

No hypoglycemic symptom

Occasional hypoglycemic symptom

Repeated hypoglycemic symptoms

12 years after operation, she died of ischemic heart disease

No data

 

Type

Diffuse

Diffuse

Diffuse

Diffuse

 

Site of the pancreas in a representative section

Tail

Tail

Body

Body

 

(B) Control cases.

 

CASE 1

CASE 2

CASE 3

CASE 4

CASE 5

Age (years)/Gender

74/F

46/F

65/M

69/M

65/M

Diseases

pulmonary vascular injury, AAV, HLH, aspergillosis, pulmonary nocardiosis

Ruptured esophageal varices, PSC, UC, LC

Systemic metastasis of prostate cancer

ICH, HT

AP, peritonitis, ALS

Site of the pancreas in a representative section

Tail

Tail

Head

Body

Body

  1. AAV, anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis; ALS, amyotrophic lateral sclerosis; ANHH, adult nonneoplastic hyperinsulinemic hypoglycemia; AP, aspiration pneumonia; DP, distal pancreatectomy; HH hyperinsulinemic hypoglycemia; HLH, hemophagocytic lymphohistiocytosis; HT, hypertension; ICH, intracerebral hemorrhaging; LC, liver cirrhosis; LOC, loss of consciousness; PSC, primary sclerosing cholangitis; TG, total gastrectomy; UC, ulcerative colitis