Circularity of islets is a distinct marker for the pathological diagnosis of adult non-neoplastic hyperinsulinemic hypoglycemia using surgical specimens

Table 3 The measured parameters and aspect ratio of the islets of ANHH and control cases

	ANHH (n = 4)	Control (n = 5)	P value
Number of islets	417 ± 67.8	501 ± 90.0	0.50
Number of islets per total area of pancreas [/cm²]	211 ± 38.6	200 ± 25.4	0.80
Total area of islets [cm²]	0.0403 ± 0.0119	0.0474 ± 0.00916	0.64
Total area of islets per total area of pancreas	2.07% ± 0.661%	1.92% ± 0.315%	0.833
Maximum diameter [µm]	107 ± 14.0	105 ± 8.97	0.89
Number of islets with circularity < 0.71	82 ± 19.0	30 ± 5.71	0.023

ISSN: 1746-1596