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Table 2 Expression of ARK5 and SIRT3 in RCC and non-neoplastic cases

From: Evaluation of ARK5 and SIRT3 expression in renal cell carcinoma and their clinical significance

 

RCC

( n  = 58)

(%)

Non-neoplastic

( n  = 30)

(%)

Test

P value

Expression

  

Fisher Exact Test

0.057

 ARK5 negative

3 (5.2%)

6 (2%)

 ARK5 positive

55(94.8%)

24 (98%)

Intracellular localization

  

Fisher Exact Test

0.001**

 ARK5 cytoplasmic

19 (34.5%)

24 (100%)

 ARK5 nucleocytoplasmic

36 (65.4%)

0 (00%)

H-score

164.5 ± 55.651

113.3 ± 65.7

Mann–Whitney

0.001**

Expression

  

Fisher Exact Test

0.002*

SIRT3 negative

14 (24.14%)

18 (6%)

SIRT3 positive

44 (75.9%)

12 (94%)

H- score

134.6 ± 81.2

59.7 ± 76.3

Mann–Whitney

0.001**

  1. *significant, **highly significant