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Table 4 Correlation of SIRT3 expression in RCC with clinicopathological parameters

From: Evaluation of ARK5 and SIRT3 expression in renal cell carcinoma and their clinical significance

 

Negative (n = 14)(%)

Positive (n = 44)(%)

Test

P value

Gender

  

Fisher Exact Test

0.53

 Male

10 (71.4%)

26 (59.1%)

 Female

4 (28.6%)

18 (40.9%)

Histological type

  

Chi square

0.21

 Clear

9 (64.3%)

23 (52.2%)

 Papillary

3 (21.4%)

4 (9.1%)

 Chromophobe

1 (7.1%)

15 (34.1%)

 Others

1 (7.1%)

2 (4.5%)

Grade

 1

4 (28.6%)

11 (25%)

Chi-square

0.17

 2

8 (57.1%)

13 (29.5%)

 3

1 (7.1%)

13 (29.5%)

 4

1 (7.1%)

7 (15.9%)

Apoptosis

2.93 ± 0.83

2.32 ± 0.86

Mann–Whitney

0.022*

Mitosis

2.1 ± 1.1

2.97 ± 1.1

Mann–Whitney

0.02*

Tumour extent

 T1

9 (64.3%)

11 (25%)

Chi-square

0.042*

 T2

4 (28.6%)

17 (38.6%)

 T3

1 (7.1%)

14 (31.8%)

 T4

0 (00%)

2 (4.5%)

LN

 negative

14 (100%)

42 (95.4%)

 

0.57

 Positive

0 (00%)

2 (4.5%)

Stage

  

Chi-square

0.039*

 I

9(64.3%)

11(25%)

  

 II

4 (28.6%)

16 (36.4%)

 III

1 (7.1%)

15 (34.1%)

 IV

0 (00%)

2 (4.5%)

Response to chemotherapy

 No

1 (7.1%)

12 (27.2%)

Chi square

0.027*

 Partial

7 (50%)

18 (40.9%)

 Complete

4 (28.6%)

2 (4.5%)

  1. *Significant