Fig. 1
From: Clinical value of Cyclin D1 and P21 in the differential diagnosis of papillary thyroid carcinoma
A Histological morphology (100 ×) and Cyclin D1 immunohistochemical staining (100 ×) of adjacent, follicular adenoma, thyroid follicular papillary hyperplasia, classical papillary carcinoma and follicular variant papillary thyroid carcinoma. A1. Histologic features of adjacent tissue; A2. Adjacent tissue does not express Cyclin D1; A3. Histologic features of follicular adenoma; A4. Follicular adenoma does not express Cyclin D1;A5. Histologic features of thyroid follicular papillary hyperplasia; A6. Thyroid follicular papillary hyperplasia does not express Cyclin D1; A7. Histologic features of classical papillary thyroid carcinoma; A8. Positive Cyclin D1 expression in classical papillary carcinoma; A9. Histologic features of follicular variant papillary thyroid carcinoma; A10. Cyclin D1 positive expression in follicular variant papillary thyroid carcinoma. B Immunohistochemical scoring of Cyclin D1 protein in 200 paired adjacent and papillary thyroid carcinomas