Table 2 Differentially-expressed ferroptosis regulators in high- and low-immune score groups
Gene.symbol | log2FC | Regulation | P.Value | adj.P.Val |
|---|---|---|---|---|
ZEB1 | -1.303268835 | Down | 1.43E-13 | 1.70E-11 |
SAT1 | 1.040029699 | Up | 6.19E-10 | 3.67E-08 |
SQSTM1 | 1.052879177 | Up | 8.80E-09 | 3.13E-07 |
NQO1 | 1.152022282 | Up | 9.25E-09 | 3.13E-07 |
MYB | 2.713284259 | Up | 1.39E-07 | 3.71E-06 |
CYBB | 1.193947248 | Up | 1.41E-07 | 3.71E-06 |
FTH1 | 1.019080646 | Up | 7.74E-07 | 1.53E-05 |
ALOX5 | 1.265722731 | Up | 1.06E-06 | 1.89E-05 |
SOCS1 | 1.128552839 | Up | 2.04E-06 | 3.03E-05 |
NCF2 | 1.439163523 | Up | 2.39E-06 | 3.29E-05 |
RELA | 1.025513027 | Up | 2.50E-06 | 3.29E-05 |
SCP2 | 1.041083389 | Up | 2.64E-06 | 3.30E-05 |
MUC1 | 1.055501129 | Up | 3.99E-06 | 4.50E-05 |
PML | 1.066477531 | Up | 5.52E-06 | 5.95E-05 |
ZFP69B | 8.44485485 | Up | 5.92E-06 | 6.10E-05 |
DPP4 | -16.60461898 | Down | 9.07E-06 | 8.96E-05 |
ANGPTL7 | 1.121711507 | Up | 1.09E-05 | 1.03E-04 |
TAZ | 1.096090796 | Up | 1.61E-05 | 1.41E-04 |
PCK2 | 1.135223683 | Up | 2.02E-05 | 1.65E-04 |
HSPB1 | 1.015436275 | Up | 2.12E-05 | 1.67E-04 |
CDKN2A | 1.093951625 | Up | 4.88E-05 | 3.73E-04 |
PRDX1 | 1.014939856 | Up | 5.34E-05 | 3.96E-04 |
ATG3 | 1.047127674 | Up | 9.54E-05 | 6.46E-04 |
PHKG2 | 1.059605756 | Up | 1.07E-04 | 6.83E-04 |
CD44 | 1.112528197 | Up | 1.16E-04 | 7.25E-04 |
PTGS2 | 1.548795188 | Up | 2.18E-04 | 1.20E-03 |
CISD2 | 1.039490309 | Up | 3.23E-04 | 1.70E-03 |
STEAP3 | 1.127225037 | Up | 3.33E-04 | 1.72E-03 |
FH | 1.024963136 | Up | 4.43E-04 | 2.11E-03 |
CHMP5 | 1.025211575 | Up | 4.48E-04 | 2.11E-03 |
MT1G | 1.115455889 | Up | 4.50E-04 | 2.11E-03 |
DDIT3 | 1.026308285 | Up | 4.54E-04 | 2.11E-03 |
CDO1 | 1.673151129 | Up | 4.87E-04 | 2.22E-03 |
LINC00472 | 1.279821228 | Up | 5.01E-04 | 2.24E-03 |
AIFM2 | 1.147153689 | Up | 7.00E-04 | 3.07E-03 |
NOS2 | 1.067585893 | Up | 8.01E-04 | 3.45E-03 |
GCH1 | 1.170107442 | Up | 1.67E-03 | 6.81E-03 |
AKR1C1 | 1.16582017 | Up | 1.72E-03 | 6.91E-03 |
CISD1 | 1.038092873 | Up | 1.82E-03 | 7.06E-03 |
HERPUD1 | 1.024418643 | Up | 2.15E-03 | 7.96E-03 |
TFAP2C | 1.063103058 | Up | 2.88E-03 | 1.02E-02 |
SLC7A11 | -5.1864395 | Down | 3.31E-03 | 1.14E-02 |
GPX4 | 1.010620025 | Up | 4.05E-03 | 1.37E-02 |
CAPG | 1.017779794 | Up | 4.61E-03 | 1.53E-02 |
LAMP2 | 1.019202163 | Up | 4.64E-03 | 1.53E-02 |
TNFAIP3 | 1.031849711 | Up | 5.24E-03 | 1.70E-02 |
NOX4 | 3.306540785 | Up | 7.09E-03 | 2.24E-02 |
GABARAPL2 | 1.033479799 | Up | 7.56E-03 | 2.36E-02 |
AKR1C2 | 1.248168752 | Up | 7.84E-03 | 2.41E-02 |
HMOX1 | 1.08061761 | Up | 9.33E-03 | 2.78E-02 |
TXNIP | 1.037383732 | Up | 9.40E-03 | 2.78E-02 |
PEBP1 | 1.013710687 | Up | 1.02E-02 | 2.95E-02 |
MAPK3 | 1.016838332 | Up | 1.37E-02 | 3.68E-02 |
IL6 | 1.802622241 | Up | 1.56E-02 | 4.14E-02 |
ATP6V1G2 | 1.487442492 | Up | 2.32E-02 | 5.92E-02 |
DUOX2 | 1.176234804 | Up | 2.33E-02 | 5.92E-02 |
PROM2 | 1.09987205 | Up | 2.45E-02 | 6.11E-02 |
YY1AP1 | 1.026722519 | Up | 2.50E-02 | 6.18E-02 |
UBC | 1.009911407 | Up | 2.65E-02 | 6.40E-02 |
BID | 1.033659428 | Up | 2.96E-02 | 7.01E-02 |
ATG7 | 1.08770804 | Up | 3.66E-02 | 8.43E-02 |
TF | 1.149335695 | Up | 4.00E-02 | 9.11E-02 |
GOT1 | 1.024804256 | Up | 4.12E-02 | 9.21E-02 |
STAT3 | 1.011819434 | Up | 4.64E-02 | 1.02E-01 |