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Fig. 3 | Diagnostic Pathology

Fig. 3

From: Sarcomatoid mesothelioma diagnosed in a patient with mesothelioma in situ: a case report on morphologic differences after 9-month interval with details analysis of cytology in early-stage mesothelioma

Fig. 3

Histological findings from the first sample (video-assisted thoracoscopic surgery biopsy for right pleura) (a–f). a, b A single layer of proliferating mesothelial cells with atypia was detected. c These mesothelial cells were positive for pan-cytokeratin (CAM5.2). d BAP1 was retained. e MTAP was lost in focal areas of the surface mesothelium. f Homozygous deletion of CDKN2A (61.5%) was detected in the surface mesothelium by fluorescence in situ hybridization (CDKN2A probe, red label; chromosome 9 centromeric probe, green label)

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Diagnostic Pathology

ISSN: 1746-1596

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