Fig. 1
From: Fluorescent in situ hybridization has limitations in screening NRG1 gene rearrangements
NRG1 fusion prevalence across cancers. A The NRG1 dual color break-apart probe is designed to detect translocations involving the chromosomal region 8p12 harboring the NRG1 gene. B Two-color FISH probes flanking the 5’-end (green) and the 30-end (orange) of the NRG1 gene were performed on the 3008 cases. C NRG1 translocation-positive cases by FISH in 3008 pancancers. D NRG1 fusion-positive cases by NGS in 3008 pancancers