Table 2 Clinicopathological characteristics of 36 patients evaluated for Pan-TRK expression

Age range

46–88 y

Median

67.5

Female

19

52.8

Male

17

47.2

HISTOLOGIC TYPE & SOURCE

SITE OF ORIGIN

Fusion positive cases (n = 9)

Secretory carcinoma of the salivary gland (MASC)

6

Parotid/salivary gland

16.8

Secretory carcinoma

1

Breast

2.8

Metastatic MEC, lung

1

Parotid

2.8

MPNST

1

Soft tissue

2.8

Fusion negative cases (n = 26)

Invasive carcinoma

1

Breast

2.8

SMARCA4-BRG-1-deficient neoplasm

1

Lung

2.8

Adenocarcinoma, lung

9

Lung

25.2

Adenocarcinoma, lung

2

Colorectal (n = 1), unknown origin (n = 1)

5.6

Polymorphous adenocarcinoma

1

Soft palate

2.8

Adenocarcinoma, lymph node

5

Lung (n = 4), urothelial (n = 1)

14

Adenocarcinoma, pericardial fluid

1

Lung

2.8

Adenocarcinoma, pleural fluid

2

Lung (n = 1), unknown origin (n = 1)

5.6

Adenocarcinoma, soft tissue

1

Lung

2.8

Adenocarcinoma, bone

2

Lung (n = 1), unknown origin (n = 1)

5.6

High grade serous carcinoma

1

Ovary

2.8

Fusion status N/A (n = 1)

Adenocarcinoma, pleura

1

Lung

2.8