Table 2 The characteristics of patients BC in different HR status in Cohort 2

Age at diagnosis

20–40

74 (19.9)

19 (16.8)

4 (36.4)

63 (16.4)

0.533

41–60

257 (69.3)

81 (71.7)

7 (63.6)

276 (71.9)

61–80

40 (10.8)

13 (1.5)

0 (0)

45 (11.7)

Surgical methods

BCS

21 (5.7)

4 (3.5)

1 (9.0)

10 (2.6)

0.153

M

350 (94.3)

109 (96.5)

10 (91.0)

374 (97.4)

Menstruatio

Yes

137 (36.9)

70 (61.9)

1 (9.0)

212 (55.2)

 < 0.001

No

234 (63.1)

43 (38.1)

10 (91.0)

172 (44.8)

BMI

 ≤ 18.5

6 (1.6)

4 (3.5)

0 (0)

9 (2.3)

0.090

18.5–24

160 (43.1)

48 (42.5)

8 (72.7)

182 (47.4)

24–30

183 (49.3)

58 (48.7)

1 (9.1)

167 (43.5)

 ≥ 30

22 (6.0)

3 (2.7)

2 (18.2)

26 (6.8)

Clinical T stage

1

45 (12.1)

17(15.0)

1 (9.1)

44 (11.4)

0.588

2

277 (74.6)

81 (71.6)

8 (72.7)

271 (70.5)

3

49 (13.3)

15 (13.4)

2 (18.2)

69 (18.1)

Clinical N stage

0

52 (14.0)

11 (9.7)

2 (18.1)

45 (11.7)

0.373

1

218 (58.7)

62 (54.8)

7 (63.8)

212 (55.2)

2

41 (11.2)

18 (16.1)

0 (0)

41 (10.6)

3

60 (16.1)

22 (19.4)

2 (18.1)

86 (22.5)

HER-2

Positive

70 (18.9)

43 (38.1)

3 (37.3)

218 (56.8)

 < 0.001

Negative

301 (81.1)

70 (61.9)

8 (62.7)

166 (43.2)

KI67

 ≤ 15

171 (46.1)

36 (29.2)

3 (37.3)

101 (26.3)

 < 0.001

 > 15

200 (53.9)

77 (70.8)

8 (62.7)

283 (73.7)

P53

0

209 (56.3)

57 (50.4)

4 (36.3)

191 (49.7)

 < 0.001

1

123 (33.1)

34 (30.0)

4 (36.3)

48 (12.5)

2

24 (6.6)

12 (10.8)

1 (9.0)

59 (15.3)

3

15 (4.0)

10 (8.8)

2 (18.4)

86 (22.5)

Histological grade

0–1

109 (29.4)

39 (34.5)

3 (37.3)

175 (45.6)

 < 0.001

2

250 (67.4)

65 (57.5)

6 (44.6)

130 (33.9)

3

12 (3.2)

9 (8.0)

2 (18.1)

79 (20.5)

Stage

I

7 (1.8)

0 (0)

0 (0)

6 (1.6)

0.359

II

238 (64.2)

67 (59.3)

7 (63.6)

220 (58.4)

III

126 (34.0)

46 (40.7)

4 (36.4)

158(40.0)

Histological type

IDC

279 (75.2)

75 (66.4)

9 (82.0)

219 (57.0)

 < 0.001

ILC

43 (11.6)

15 (13.3)

1 (9.0)

53 (13.8)

Others

49 (12.2)

23 (20.3)

1 (9.0)

112 (29.2)