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Fig. 2 | Diagnostic Pathology

Fig. 2

From: Ovarian non-gestational placental site trophoblastic tumor with lung metastasis: further evidence for a distinct category of trophoblastic neoplasm

Fig. 2

Non-gestational placental site trophoblastic tumor (PSTT) in the ovary. Section demonstrated a mass lesion with solid and cystic growth pattern and hemorrhage (A). The tumor was composed of singly dispersed predominantly mononuclear cells extensively infiltrating the ovarian parenchyma (B). A minor component of mature cystic teratoma was present (B). The tumor cells displayed perivascular accentuation around the arteries and replacement of the vascular wall of veins (C). The hemorrhagic areas contained loosely cohesive tumor cells (D). On high power, the polygonal tumor cells showed irregular and hyperchromatic nuclei, occasional nuclear pseudoinclusions, and abundant eosinophilic to amphophilic cytoplasm (E). The tumor diffusely involved fallopian tube mucosa (F)

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