Comprehensive evaluation of the relationship between biomarker profiles and neoadjuvant chemotherapy outcomes for breast cancer patients

Table 3 Linear regression analysis of the relationship between the tumor size change and biomarkers

	Test	n	Coefficient	p-value
HER2	Linear regression for dummy variable	189	Not significant	> 0.2
ER	Linear regression for dummy variable	189	0.3184	< 0.001*
PR	Linear regression for dummy variable	189	0.2821	< 0.001*
TOPO II	Linear regression for dummy variable	118	Not significant	> 0.2
EGFR	Linear regression for dummy variable	120	Not significant	> 0.05
Ki67	Linear regression	189	-0.0044	0.003*
CK5/6	Linear regression for dummy variable	116	Not significant	> 0.05
AR	Linear regression	134	Not significant	> 0.5
P53	Linear regression	119	Not significant	> 0.2

p-value is the P >|t| value associated with the model coefficient(s)
n is the number of patients having the according information therefore used for regression analysis
*differences are considered statistically significant at a p-value of less than 0.05

ISSN: 1746-1596